Sex is a major determinant in disease prevalence and treatment response, caused by a vast number of genetic differences between men and women. However, the inclusion of both sexes in clinical and scientific research had not been mandated by federal law until nearly the turn of the century.
October 2023 Breakthroughs newsletter feature story
“The Rise and Fall of Animal Experimentation: Empathy, Science, and the Future of Research”
Written by Richard Miller, emeritus professor of Pharmacology, "The Rise and Fall of Animal Experimentation" details the history of animal experimentation – from its early beginnings in the 17th century through present day – citing diverse scientific, theological and philosophical bases for its use. Miller discusses important cutting-edge alternatives to the use of animals in biomedical research and examines the utility of animal research through a scientific lens.
At Feinberg, scientists across various disciplines are improving the efficiency of breast cancer detection through AI and machine learning, investigating disparities in patient outcomes and identifying new precision medicine strategies through robust clinical, basic science and population-health research.
May 2023 Breakthroughs feature story
Faculty Profile: Understanding and Improving Variant Interpretation in Minoritized and Underserved Populations
The Gordon laboratory investigates the implementation of genomic testing in medical and consumer contexts, and the process of variant interpretation that seeks to translate this testing into actionable clinical findings.
At Feinberg, scientists are pursuing synthetic biology research to address the health challenges and diseases that humans face.
November 2022 Breakthroughs feature story
Alfred George, Jr., MD, is a pioneer in understanding the mechanisms by which ion channel mutations cause a variety of inherited disorders, such as genetic epilepsy. He discusses his recent breakthroughs in the field and his optimism for future RNA therapeutics to treat rare genetic diseases.
A chemical modification of messenger RNA (mRNA) performs different functions depending on its location, according to a study published in the journal Molecular Cell.
Northwestern Medicine continues to help advance the understanding of the COVID-19 pandemic and its widespread impact, from investigating antibody protection against COVID-19 reinfection to elevating women in academic research to highlighting racial and ethnic disparities in COVID-19 hospital mortality in Illinois.
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