News and Announcements
Read the latest news from Northwestern University Feinberg School of Medicine’s Department of Pharmacology and learn more about our faculty’s latest achievements, awards and honors.
- 11.07.2024
In research published in Science Advances, scientists at Northwestern and Case Western Reserve universities have developed the first polymer-based therapeutic for Huntington’s disease, an incurable, debilitating illness that causes nerve cells to break down in the brain.
- 10.24.2024
Scientists have discovered an RNA that controls how much or how little protein is produced by a gene, with implications for neurodevelopmental disorders like epilepsy and autism.
- 06.10.2024
Northwestern Medicine investigators have identified novel genetic mechanisms that regulate blood vessel growth in the retina and may also serve as therapeutic targets for retinal vascular disease, according to findings published in Nature Communications.
- 06.03.2024
Northwestern Medicine scientists have been awarded $17 million to study genetic causes of autism and schizophrenia, with the aim of developing new drugs to treat the conditions.
- 05.23.2024
Northwestern Medicine scientists have developed a new method of measuring and optimizing the maturation process of cultured heart cells, an approach that will set the future standard for a commonly used cell model in scientific research, according to details published in Cell Reports.
- 04.17.2024
A multi-institutional team of investigators have developed a new framework for supporting healthcare providers in implementing polygenic risk score-based testing into primary care settings, according to a recent study published in Nature Medicine.
- 03.25.2024
Northwestern Medicine scientists have developed a method to identify and characterize microproteins, a development which opens the door for understanding physiology and disease at a molecular level not possible until now, according to findings published in Nature Communications.
- 02.23.2024
A multidisciplinary team of investigators have engineered a more accurate model for studying the underlying mechanisms of atrial fibrillation and treatment response, according to findings published in Science Advances.
- 02.22.2024
Scientists have discovered a neuronal pathway involved in how the brain encodes the transition to high-intensity fear response behaviors required for survival, according to a study published in Nature.
- 12.14.2023
Northwestern Medicine scientists have developed a deep learning algorithm accelerating research around diseases and disorders that occur when the process of DNA transcription goes awry.
- 11.16.2023
A new molecular technology capable of binding to mRNA and regulating gene expression may offer a new avenue for treating diseases caused by insufficient protein levels, according to a study published in Nature Communications.
- 10.11.2023
A novel cellular pathway regulates DNA damage and structural changes in cardiomyocytes which contributes to the development of cardiac hypertrophy according to a Northwestern Medicine study published in Circulation.
- 09.25.2023
Northwestern Medicine investigators have uncovered new mechanisms by which iron deficiency inhibits cell growth and proliferation in eukaryotic cells, findings that could improve the understanding of cancer growth and the development of targeted cancer therapies.
- 09.14.2023
Northwestern Medicine investigators have identified how a calcium channel in the nervous system contributes to brain inflammation, according to a study published in Nature Communications.
- 08.21.2023
A new Northwestern Medicine study has discovered a novel therapeutic target and therapeutic agents for older patients with acute respiratory distress syndrome, according to recent findings published in Science Translational Medicine.
- 08.16.2023
More cases of children born with abnormal brain development may have genetic explanations than previously thought, according to a recent study published in JAMA Neurology.
- 07.19.2023
Northwestern Medicine scientists have developed a new technique for measuring protein folding stability on an unprecedented scale, according to a new study published in Nature.
- 06.15.2023
Reduced expression of specific calcium channels impaired electrical signaling between neurons and contributed to the onset of behaviors associated with neurodevelopmental disorders and seizure susceptibility in mouse models, according to a Northwestern Medicine study.
- 06.09.2023
Investigators have discovered that a subset of sensory neurons promote osteoarthritis-related joint pain and inflammation, suggesting a new therapeutic target for pain management, according to findings published in Nature Communications.
- 06.05.2023
Northwestern Medicine investigators have discovered novel features of circulating tumor stem cells that can promote chemotherapy evasion and metastasis in triple-negative breast cancer, according to a recent study.
- 05.11.2023
Investigators led by Barbara Stranger, PhD, associate professor of Pharmacology, developed a guide outlining best practices for studying and testing sex-dependent genetic effects in complex traits and diseases, published in the journal Cell.
- 02.07.2023
Northwestern Medicine investigators have identified new genetic variations effecting gene expression in the liver cells of patients of African descent, findings that provide insight into how drugs are metabolized differently in different populations.
- 02.06.2023
Targeting calcium signaling in neurons may represent a promising therapeutic approach for treating a rare form of schizophrenia, according to a Northwestern Medicine study.
- 01.27.2023
Northwestern Medicine investigators have discovered that specific calcium channels help regulate sex differences in the functioning of immune cells for neuroinflammation and overall neuropathic pain.
- 12.26.2022
A team of Northwestern investigators led by Peter Penzes, PhD, has developed a new therapy that could treat Phelan-McDermid syndrome, a subtype of autism spectrum disorder.
- 10.27.2022
Northwestern Medicine investigators have developed a novel approach for designing and testing new protein folds, which could be used to develop new therapeutics.
- 10.14.2022
Using machine learning, Northwestern scientists have demonstrated that the protein membrane CD81 interacts with CD44 in promoting tumor cell cluster formation and lung metastasis of triple negative breast cancer.
- 10.04.2022
Therapeutically targeting ion channels in nociceptor neurons may be a promising strategy for managing osteoarthritis pain, according to a Northwestern Medicine study.
- 08.05.2022
An immune system kinase promotes tumor inflammation and progression, according to a study published in Nature Communications.