Northwestern University Feinberg School of Medicine
Department of Pharmacology
Ryan M Drenan, PhD

Ryan M Drenan, PhD

Associate Professor of Pharmacology

Focus of Work

Bio

We study the physiological processes regulated by native nicotinic acetylcholine receptors (nAChRs), a large family of ligand gated ion channel proteins. These receptors mediate key aspects of cholinergic signaling in the brain, and are involved in several important cognitive processes, including motivated behavior, affective behavior, attention, and learning/memory. Aberrant nAChR activity is linked to several neurological diseases/disorders, such as nicotine addiction, schizophrenia, major dep...[Read full text]We study the physiological processes regulated by native nicotinic acetylcholine receptors (nAChRs), a large family of ligand gated ion channel proteins. These receptors mediate key aspects of cholinergic signaling in the brain, and are involved in several important cognitive processes, including motivated behavior, affective behavior, attention, and learning/memory. Aberrant nAChR activity is linked to several neurological diseases/disorders, such as nicotine addiction, schizophrenia, major depressive disorder, Alzheimer's disease, and Parkinson's disease. We utilize a broad range of techniques, including patch clamp electrophysiology, confocal and two-photon imaging, immunohistochemistry, and behavioral approaches.[Shorten text]

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Education and Certification

  • PhD: Washington University, Molecular Cell Biology (2006)
  • Postdoctoral Fellowship: California Institute Of Technology (2010)

Contact

312/503-4892

Searle Building Room 8-510
320 E Superior
Chicago IL 60611