The links below take you to articles and announcements about our faculty’s latest achievements, awards, and major publications, as well as to significant discoveries in our field.
Northwestern Medicine scientists identified the process by which a calcium channel called the CRAC channel opens and closes, and how mutations in the channel structures that control its opening cause disease.
A new Northwestern Medicine study may help explain why patients with the same epilepsy gene mutation experience different levels of disease severity. The findings, published in the Proceedings of the National Academy of Sciences (PNAS), also reveal new insights into sodium channel regulation and a potential therapeutic target for epilepsy treatment.
Christopher Thompson, PhD, research assistant professor of Pharmacology, was the first author of the study, led by principal investigator Alfred George, Jr., MD, chair and Magerstadt Professor of Pharmacology.
Northwestern Medicine scientists have identified the unique targets of two enzymes that activate ubiquitination, a key modification of proteins that controls a variety of cellular processes.
- Department of Pharmacology Ranked 10th in NIH Funding01.25.2017The Department of Pharmacology is ranked 10th among similar departments for the National Institutes of Health (NIH) funding in 2016. The rankings are reported annually by the Blue Ridge Institute for Medical Research.
The current ranking marks a significant advancement for the department in a short time frame. The department has increased position from the speciality mid-range (~50th) over the past few years.
Alfred L. George Jr., MD, Magerstadt Professor and Chair, Department of Pharmacology, joined Feinberg on March 1, 2014. He notes that the surge in rankings has been fueled by both new faculty hires as well as the success of all faculty in acquiring or maintaining existing funding.
“Our department has enjoyed tremendous growth and research prosperity recently owing to the great effort by the faculty coupled with strong support from the Dean of Feinberg,” said George. “We look forward to achieving further milestones as we work together to build a top ranked 21st century department of Pharmacology”
Northwestern University Feinberg School of Medicine rose to 16th place among U.S. medical schools in funding from the NIH in 2016. Learn more regarding the current rankings.
Former and current colleagues, students and friends gathered to celebrated the career of Paula Stern, PhD, an authority on bone and mineral health research, and a respected leader and educator.
Northwestern Medicine scientists have demonstrated an alternate method of signaling used by proteins called group I metabotropic glutamate receptors, a finding that could be used to develop novel drug treatments for many neurological disorders.
A new study shows potential mechanisms leading to the activation of a mutated gene in autosomal dominant polycystic kidney disease.
- 11.17.2016Through her research, Minoli Perera, PharmD, PhD, associate professor of Pharmacology, works to bring pharmacogenomics to African-American populations. Pharmacogenomics, part of the precision medicine movement, involves using a patient’s genetic information to predict drug response, such as whether the medication will be effective or if it might lead to adverse effects.
- Richard Miller, PhD discusses the cultural importance of the psychoactive mushroom fly agaric with Brett Westwood, "Natural Histories," BBC Radio 411.16.2016
On this episode of the BBC Radio 4 program "Natural Histories," Brett Westwood seeks out the mushroom fly agaric, with its iconic red cap and white spots. The story of fly agaric is entwined with Father Christmas, Alice in Wonderland and the founding of religion itself. The mushroom'shallucinogenic properties and its appearance in fairy tales make it the most evocative of all British fungi. Brett goes into the woods with River Cottage forager John Wright and talks to Richard Miller, PhD and Dr. Patrick Harding about its surprising importance in human culture.
In a study published in in Nature Medicine, Northwestern Medicine scientists identified an enzyme as a potential new target for triple-negative breast cancer (TNBC), a form of breast cancer that is associated with early tumor recurrence and significantly increased mortality rates when compared to receptor-positive breast cancers.
Northwestern Medicine scientists co-authored a study that identified a blood cell not normally found in the healthy brain that can invade brain tissue after status epilepticus, a type of seizure, and contributes to inflammation.
- 09.08.2016September 2016 issue of Breakthroughs, the Feinberg School of Medicine Research Office newsletter.
Northwestern Medicine scientists have received a $7.5 million grant to study how genetic information from African American patients can predict their responses to medications.
- 08.19.2016August 2016 issue of Breakthroughs, the Feinberg School of Medicine Research Office newsletter.
New Northwestern Medicine research has shown that reprogrammed stem cells can be used to identify patients with cancer who are likely to experience a dangerous side effect of a common chemotherapy drug.
In a new study, patients treated with one-fourth of the dose of beta-blockers tested in large clinical trials had a 20 to 25 percent increase in survival, indicating that dosing likely needs to be personalized for patients to get the best benefit.
A trail of messenger molecules left behind by general immune system cells called neutrophils helps virus-specific T-cells reach tissues infected by influenza, reports a new study published in Science.
Northwestern Medicine scientists received a five-year, $3.9 million grant from the National Institutes of Health to determine the optimal drug doses for treating pregnant women with depression.
Northwestern Medicine scientist Jeffrey Savas, PhD, and colleagues identified a receptor that sorts proteins in synapses, a finding that may augment future treatments for multiple neurological diseases and disorders.
Northwestern Medicine scientists investigated the mechanism behind a mutation in a calcium ion channel that leads to an immunodeficiency syndrome.
Northwestern Medicine scientists, inspired by treatments used by traditional healers in Nigeria, have synthesized four new chemical compounds that may lead to therapies for psychiatric disorders.