News and Announcements

A multi-institutional team of investigators have developed a new framework for supporting healthcare providers in implementing polygenic risk score-based testing into primary care settings, according to a recent study published in Nature Medicine.

A multidisciplinary team of investigators have engineered a more accurate model for studying the underlying mechanisms of atrial fibrillation and treatment response, according to findings published in Science Advances.

Northwestern Medicine scientists have developed a deep learning algorithm accelerating research around diseases and disorders that occur when the process of DNA transcription goes awry.

A novel cellular pathway regulates DNA damage and structural changes in cardiomyocytes which contributes to the development of cardiac hypertrophy according to a Northwestern Medicine study published in Circulation.

Northwestern Medicine investigators have uncovered new mechanisms by which iron deficiency inhibits cell growth and proliferation in eukaryotic cells, findings that could improve the understanding of cancer growth and the development of targeted cancer therapies.

Geoffrey Swanson, PhD, professor of Pharmacology, has been named the new vice chair of Pharmacology, effective September 1. In this new role, Swanson will be responsible for overseeing faculty development among early and mid-career faculty members and will contribute to the strategic direction of graduate student and postdoctoral fellow training. Swanson will also lead the departmental promotions and tenure committee while actively contributing to the department’s strategic planning efforts.

More cases of children born with abnormal brain development may have genetic explanations than previously thought, according to a recent study published in JAMA Neurology.

Reduced expression of specific calcium channels impaired electrical signaling between neurons and contributed to the onset of behaviors associated with neurodevelopmental disorders and seizure susceptibility in mouse models, according to a Northwestern Medicine study.

Northwestern Medicine investigators have discovered novel features of circulating tumor stem cells that can promote chemotherapy evasion and metastasis in triple-negative breast cancer, according to a recent study.

Investigators led by Barbara Stranger, PhD, associate professor of Pharmacology, developed a guide outlining best practices for studying and testing sex-dependent genetic effects in complex traits and diseases, published in the journal Cell.

Targeting calcium signaling in neurons may represent a promising therapeutic approach for treating a rare form of schizophrenia, according to a Northwestern Medicine study.

A team of Northwestern investigators led by Peter Penzes, PhD, has developed a new therapy that could treat Phelan-McDermid syndrome, a subtype of autism spectrum disorder.

Using machine learning, Northwestern scientists have demonstrated that the protein membrane CD81 interacts with CD44 in promoting tumor cell cluster formation and lung metastasis of triple negative breast cancer.

An immune system kinase promotes tumor inflammation and progression, according to a study published in Nature Communications.

An enzymatic modifier of messenger RNA has different functions depending on its location, according to a recent study.