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POEM Chicago Signaling 20 |
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Twenty years it been since we first
Signaled, second city. Each year since then the science has been Both elegant and pretty. First Susan Taylor spoke to us, The mom of PKA. A structured tour de force she gave Great way to start the day. The kinase family, A G C, Has tails quite conserved. They bind the CAT, but cyclic A, Elicits them to swerve. Wonwha Cho next surfaced and he Waxed on membrane lipids. He showed how proteins, soluble, Docked and turned up PIPed Kif 16B is Atlas-like,Drags vesicles within. And METADOR predicts proteins That gore the lipid skin. Next Dohlman did make sure we knew Yeast do more than make beer. Their mating has been studied much And G proteins do steer An inward course to endosomes, And kinase, P13. Explains why QL mutant cells, Are schmoozing endlessly. Gutkind spoke about Kaposis It's neither good nor kind. GPCRs from viruses A cascade then unwind, |
Of vessels that make tumors grow. A K T saves the day. Find compounds targeting mTOR, And tumors melt away. Next we had a little lunch, Took in a bit of sun, Saw some outstanding posters and I guess we all had fun. Returned from lunch, to Sonnenberg, With great anticipation. We heard a talk that suffered none From aspects of translation. The five prime cap of RNA Binds E I F 4 E, Suppressing transformed growth in cells, To make us tumor-free. And last we heard from Lou Reichardt 'Bout signalsat the synapse. When they don't function perfectly, Acts both good and sin lapse. Catenin and cadherin line. The membrane, pre-synaptic. They look for where the actin is Results are quite fantastic. Well, that's it for today, my friends. We've made it through our teens. I guess it's time that we grow up Trade khaki's for our jeans, And leave this meeting feeling well. This day has been quite great. Let's meet next year for 21, With bated breath we'll wait. |
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Mark M. Rasenick, 24 May 2007
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